Field Effect Transistor Biosensors

High Sensitivity, High Selectivity Detection of Biomarker Proteins

Charge transfer between bio target molecule, receptor, and gate region of semiconductor transistor produces state-of-the-art performance and lifetime

Distance - Dependent Charge Transfer and Gate Capacitance

Site-Selective Current Sensitivity Only To Analyte in Solution


  • S. C. Lee, M. T. Keener, D. R. Tokachichu, B.Bhushan, P. D. Barnes, B. R. Cipriany, M. Gao, and L. J. Brillson, "Protein Binding on Thermally Grown Silicon Dioxide," J. Vac. Sci. Technol. B23, 1856 (2005); Virtual J. Biolog. Phys. 10 (4) (2005).

  • T. R. Nicholson III, S. Gupta, X. Wen, H.-H. Wu, A. Ramish, P. Casal, K. J. Kwak, B. Bhushan, P. R. Berger, W. Lu, L. J. Brillson, Stephen Craig Lee, "Rational enhancement of nanobio-technological device function illustrated by partial optimization of a protein sensing field effect transistor Proc." IMechE, Part N: J. Nanoengineering and Nanosystems 223, 149 (2010)